翻訳と辞書 Words near each other ・ Protein I-sites ・ Protein IB5 ・ Protein Information Resource ・ Protein inhibitor of activated STAT ・ Protein inhibitor of activated STAT2 ・ Protein isoform ・ Protein K ・ Protein K (gene expression) ・ Protein K (porin) ・ Protein kinase ・ Protein kinase A ・ Protein kinase B ・ Protein kinase C ・ Protein kinase C zeta type ・ Protein kinase D1 ・ Protein kinase domain ・ Protein kinase inhibitor ・ Protein kinase N1 ・ Protein kinase R ・ Protein kinase, AMP-activated, alpha 1 ・ Protein L ・ Protein ligand ・ Protein Local Optimization Program ・ Protein losing enteropathy ・ Protein M ・ Protein mass spectrometry ・ Protein metabolism ・ Protein methods ・ Protein methylase I ・ Protein methylation Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Protein kinase domain ： ウィキペディア英語版 Protein kinase domain The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. Protein kinases are a group of enzymes that move a phosphate group onto proteins, in a process called phosphorylation. This functions as an on/off switch for many cellular processes, including metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. They also function in embryonic development, physiological responses, and in the nervous and immune system. Abnormal phosphorylation causes many human diseases, including cancer, and drugs that affect phosphorylation can treat those diseases.〔(G. Manning, D. B. Whyte, R. Martinez, T. Hunter, S. Sudarsanam, The Protein Kinase Complement of the Human Genome ), ''Science'' 6 December 2002, 298:1912-1934 〕 Protein kinases possess a catalytic subunit which transfers the gamma phosphate from nucleoside triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. These enzymes fall into two broad classes, characterised with respect to substrate specificity: serine/threonine specific and tyrosine specific. ==Function== Protein kinase function has been evolutionarily conserved from ''Escherichia coli'' to ''Homo sapiens''. Protein kinases play a role in a multitude of cellular processes, including division, proliferation, apoptosis, and differentiation. Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Protein kinase domain」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.